Melanoma Organoid Model

Melanoma PDX models, or patient-derived xenograft models, are crucial in advancing our understanding of melanoma and developing targeted therapies. By transplanting melanoma tumor tissues from patients into immunocompromised mice, researchers can replicate the complex architecture and genetic diversity of human tumors. These models maintain the unique histological and molecular characteristics of the original melanoma, providing a valuable platform for preclinical testing of new drugs and personalized medicine strategies. Melanoma PDX models are instrumental in exploring tumor behavior, drug resistance mechanisms, and therapy responses, offering a pathway to more effective treatments and improved outcomes for patients battling this aggressive form of skin cancer.